Sean Cassidy

Co-Founder and CEO
Lucem Health
Raleigh, NC
Sean Cassidy 1

20+

Years In Healthcare

1

Startups Initiated 

2,072

LinkedIn Followers

Sean's Journey

Began his career as a Senior Consultant at Andersen Consulting.

1993

Joined Premier healthcare alliance as General Manager of Enterprise Provider Analytics.

2012

Became CEO of Corepoint Health, leading the company through a successful merger with Rhapsody Health that formed what is now Lyniate.

2018

2010

Joined IBM Software Group as Director of Healthcare Products and Information Management, leading healthcare product strategy for IBM’s largest software division.

2017

Joined SA Ignite (now SPH Analytics) as acting Chief Product Officer and Advisor, leading strategy, product management, engineering, and IT operations.

2021

Co-founded Lucem Health as CEO alongside Mayo Clinic, General Catalyst’s Commure, and Rally Ventures, with a mission to revolutionize care delivery through the practical application of clinical AI.

About Lucem Health

Founded - 2021 | Raleigh, NC | Stage - Series A/Growth

Highlight

Lucem Health helps healthcare providers deploy practical clinical AI for earlier disease detection and care workflow improvement.

Problem

Healthcare AI often stalls after model development because providers struggle to integrate predictions into real clinical workflows. Disease risk signals are only valuable if clinicians can act on them in time.

USP

Lucem was co-founded with Mayo Clinic and focuses on practical, responsible AI for care delivery. It has raised Series A funding and built disease-detection solutions across lung cancer, colorectal cancer, liver disease, arrhythmias, and Type 1 diabetes.

In Sean’s words, the company was ‘born at Mayo Clinic, built for the real world,’ which reflects Lucem Health’s a model of bringing actionable clinical AI to the point of care.

Key Milestones

2021

Founded in Raleigh to operationalize clinical AI in healthcare workflows.

2023

Raised $7.7 million in Series A funding with backing from Mayo Clinic and other investors.

2024

Continued developing AI-powered disease detection and care workflow products.

2025

Announced initiatives around early detection, including type 1 diabetes risk.
Named Rising Star winner for AI in Health Operations at the Digital Health Hub Awards at HLTH.
In Their Own Words:

"Accelerate disease detection and treatment using practical, responsible AI."